I question many aspects of the whole "it's genetic, I can't help it".
While it's certainly true that many overweight kids have overweight parents, the fact that there's regional and cultural components to obesity that are far more pronounced leads me to think that behavior is driving more of our obesity problem than genetics.
For the regional component...
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It's not as if the people in Colorado are vastly genetically different than their counterparts 2 states away over in Arkansas.
Now, being someone who has half of the family that's Southern Baptist, and half of the family that's Catholic (with one tiny branch off of my Dad's side that are practicing Jews), this one I found interesting with regards to food culture.
(this is a little older, it's from 2008)
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My extended family would fit this data almost perfectly.
My mom's side nearly half of them that are Obese, my Dad's side, not as many. (and the small branch of the family that are Jews practicing and following a Kosher diet all look pretty svelte)
We were raised Southern Baptist, I remember the pot luck meals that took place after every Sunday service and after every Wednesday night prayer meeting. (it would put Golden Corral to shame)
...and when we'd visit my mom's side of the family down south, I swear they wouldn't even touch a vegetable unless is was deep fried or swimming in butter.
My theory on that?
The practicing Jews stay thinner due to the stricter rules regarding keeping Kosher (things like Bacon Cheeseburgers, Bacon, and Pepperoni pizza are a no-go)
On the Catholic side of the family, they have -- for lack of a better way of putting it -- more "options of vice" (aka: they can have a few drinks at get togethers to have fun) ...whereas, in the strict side of the Baptist part of the family, no beer, no secular music, no watching movies, no fun video games... you cut out all of the things that are fun, what pleasurable experience is left? Eating.
Absent some extraordinary hormonal or medical issue, nobody, even sedentary, is bulking up to 350+ on a 2500 (or even 3000) calories per day -- given that the rule of them is to gain one pound of body weight, you need to consume 3500 calories over your caloric maintenance limit (and your BMR increases with your weight), I thought this was an interesting one to run through Claude's AI (since it's just a mathematical exercise) leveraging the Mifflin–St Jeor formula.
If a 30 year old was 6 foot and 180 pounds, they'd have to consume 4,500 calories a day (almost twice the BMR) regularly for nearly 2 years before approaching 350.
So this stuff isn't happening to people overnight. There are undoubtedly several iterations of having to go up in pants size over a period of years.