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Fitness, Health & Nutrition
A ketogenic diet with exercise improve mitochondria and metabolic health
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<blockquote data-quote="FireDragon76" data-source="post: 77497228" data-attributes="member: 330042"><p>No. The single APOE4 polymorphism places her at somewhat elevated risk of cardiovascular disease and Alzheimer's, but her diabetes risk is normal.</p><p></p><p></p><p></p><p>The APOE4 polymorphism can cause problems in cholesterol metabolism. Usually, people with the genes are advised to minimize consumption of saturated fat and refined carbohydrates, and focus on unsaturated fats found in nuts or fruits (avocados and olives). Soluble fiber supplements or regularly eating foods like oatmel is also recommended, to help lower cholesterol further. Often, statin drugs are needed if dietary changes aren't enough.</p><p></p><p>When we initially tried the keto diet, we didn't know she has the polymorphism, we only found out through doing 23andMe gene sequencing.</p><p></p><p>There's a well-known fitness influencer, Dr. Peter Attia, that also has the APOE4 polymorphism. It's uncommon but not too rare. Dr. Attia takes two statin drugs to deal with his condition, but he doesn't follow any special diet, except he avoids junk food.</p></blockquote><p></p>
[QUOTE="FireDragon76, post: 77497228, member: 330042"] No. The single APOE4 polymorphism places her at somewhat elevated risk of cardiovascular disease and Alzheimer's, but her diabetes risk is normal. The APOE4 polymorphism can cause problems in cholesterol metabolism. Usually, people with the genes are advised to minimize consumption of saturated fat and refined carbohydrates, and focus on unsaturated fats found in nuts or fruits (avocados and olives). Soluble fiber supplements or regularly eating foods like oatmel is also recommended, to help lower cholesterol further. Often, statin drugs are needed if dietary changes aren't enough. When we initially tried the keto diet, we didn't know she has the polymorphism, we only found out through doing 23andMe gene sequencing. There's a well-known fitness influencer, Dr. Peter Attia, that also has the APOE4 polymorphism. It's uncommon but not too rare. Dr. Attia takes two statin drugs to deal with his condition, but he doesn't follow any special diet, except he avoids junk food. [/QUOTE]
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A ketogenic diet with exercise improve mitochondria and metabolic health
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